What is Vigamox®?
Vigamox® is a sterile topical ophthalmic solution comprising 8-methoxy fluoroquinolone anti-infective product.
How Does Vigamox® Work?
Vigamox® inhibits the topoisomerase IV. DNA gyrase is an essential enzyme involved in the replication, transcription, and repair of DNA. Topoisomerase is an essential enzyme in the partitioning of the chromosomal DNA during bacterial cell division.
Reasons for Using Vigamox®
Vigamox® is indicated for the treatment of bacterial conjunctivitis caused by susceptible strains of the following bacteria:
Aerobic Gram-Positive Bacteria
Staphylococcus viridians group
Aerobic Gram-Negative Bacteria
Contraindications for Vigamox®
Vigamox® is contraindicated in people with a history of hypersensitivity to moxifloxacin, other quinolones, or components of this product.
Side effects and Precautions for Vigamox®
As with other anti-infectives, prolonged use may cause over growth of non-susceptible bacteria or fungi.
Vigamox® can cause a hypersensitivity reaction and should be discontinued immediately and contact your eye doctor.
Pregnant women should not use Vigamox® unless the potential benefits outweigh the risks as there are no adequate studies for the use during pregnancy.
Nursing mothers should not use Vigamox® unless the potential benefits outweigh the risks as there are no adequate studies for the use while nursing.
Vigamox® has not been studied in infants under 1 year.
Ocular Side Effects Occurred in Less Than 6 %:
Blurred vision, conjunctivitis, eye discomfort, dry eyes, keratitis, itching, epiphora (tearing), and subconjunctival hemorrhage.
Non-Ocular Side Effects Occurred in 1-4%:
Fever, infection, cough, otitis media, pharyngitis, rash, and rhinitis (runny nose).
Administration and Strength of Vigamox®
The recommended dosage is one drop in the affected eye or eyes 3 times a day. It comes in 0.5% strength.
How is Vigamox® Supplied?
Vigamox® is supplied in a sterile ophthalmic dispensing bottle with 3mL in a 4mL container.