Latisse is a prostaglandin analog used for the treatment of hypotrichosis. It increases the length, thickness and darkness of the eyelashes. The FDA approved Latisse for the treatment of hypotrichosis in 2008. The drug was first used in treating glaucoma in 2001 and it was noted that these people developed longer and fuller eyelashes. The original drug was called Lumigan® (bimatoprost ophthalmic solution) 0.03%.
The precise method of action is not known but it is thought to increase the number of eyelashes in and increase the duration of the anagen or growth phase.
Side Effects and Precautions for Latisse
Effects on Intraocular Pressure
Latisse or Lumigan lowers intraocular pressure when it is instilled onto the eye. Latisse lowers the intraocular pressure when applied on the eyelids but not enough to cause any clinical concern.
Increased Iris Pigmentation
Increased iris pigmentation has been shown to occur. There is an increase in the melanin not an increase in the number of melanocytes.
Increased Eyelid Pigmentation
Bimatoprost has been shown to increase in pigmentation or darkening in the periorbital area. It has been shown to be reversible in many patients after discontinuing the medication.
Hair Growth Outside the Treatment Area
There is a possibility of hair growth outside the eyelash area with repeated contact on the skin. You should be careful about getting any of the medication on any other area of skin and to blot it off if it occurs.
There have been reports of exacerbation of active intraocular inflammation with using Bimatoprost.
Contact Lens Use
Contacts should be out of the eye before applying Latisse.
Use in Pregnancy and Nursing Mothers
Use in these populations should only be done if the potential benefits outweigh the risks.
These side effects occurred in less than 4%;
Dry eye symptoms
Similar side effects associated with Lumigan could possibly occur and can be found by looking for the medication on another page.
Administration of Latisse
Make sure that the face is clean. Once nightly, place one drop of Latisse on the disposable sterile applicator and evenly apply it along the skin of the upper eyelid margin at the base of the eyelashes. Blot any excess off any other areas of the skin. Dispose of the applicator after each use. Repeat the process for the other eyelid.
How is Latisse Supplied?
Latisse is supplied in a sterile dispenser bottle with 60 sterile disposable applicators.