What is Azasite®?
Azasite® is a topical ophthalmic macrolide antibiotic.
How Does Azasite® Work?
Azasite® works by binding to the 50S ribosomal subunit of susceptible bacteria which interferes with microbial protein synthesis.
Reasons for Use of Azasite®
Azasite® is indicated in the treatment of bacterial conjunctivitis (pink eye). It also has been used extensively for the treatment of blepharitis.
Side Effects and Precautions for Azasite®
Patients who are known to be sensitive to azithromycin and erythromycin should not use Azasite®.
Prolonged use of Azasite® may result in over-growth of non-susceptible organisms including fungi.
Patients should not wear contact lenses if they have a bacterial conjunctivitis.
Azasite® has not been studied in pediatric patients under age 1 and should be used with caution.
Side Effects Reported in the Original Clinical Study
1 to 2 % of Patients
Less than 1% of Patients
Post Marketing Reports of Side Effects
Allergic reactions include facial swelling, hives, periocular swelling, rash, and urticaria.
Clinical Study Results
The microbiological success rate for the eradication of the baseline bacteria was 88% after 1 week of use.
Administration and Strength of Azasite®
One drop of Azasite® 1% ophthalmic solution is instilled 2 times daily for the first 2 days into the affected eye. Azasite® is then instilled 1 time a day for 5 days.
How is Azasite® Supplied?
Azasite® is supplied in a 5mL ophthalmic dispensing bottle containing 2.5 mL of 1% Azasite® sterile solution.