What is Alocril®?
Alocril® is a sterile yellow ophthalmic solution that is a mast cell stabilizer.
How Does Alocril® Work?
Alocril® is a mast cell stabilizer. Mast cells release chemical substances that are responsible for the effects from allergic reactions. Alocril® inhibits the release of these inflammatory mediators from the mast cells. This results in decreased chemotaxis and decreased activation of eosinophils in the body.
Reasons for the Use of Alocril®
Alocril® is indicated for the treatment of ocular itching related to allergic conjunctivitis.
Contraindications for Alocril®
Alocril® is contraindicated in people who have a known allergy to Alocril® or any of the ingredients in Alocril®.
Side Effects and Precautions for Alocril®
Patients should not instill Alocril® while wearing contact lenses.
Patients should not wear contact lenses while their eyes are red or inflamed from an allergic reaction.
Alocril® has not been adequately studied in pregnant women and should only be used if the potential benefits outweigh the risks of using Alocril®.
It is not known if Alocril® is excreted in human milk and therefore should only be used if the potential benefits outweigh the risks.
Side Effects in 40% of Patients
Headaches in patients were the most common reported side effect.
Side Effects in 10-30% of Patients
Burning, stinging, and irritation of the eyes, unpleasant taste, and nasal congestion were reported in patients.
Side Effects between 1-10% of Patients
Conjunctivitis, redness, light sensitivity, rhinitis, and asthma were reported in patients.
Administration and Strength of Alocril®
Alocril® comes in only one strength of 2%. The administration of Alocril® is one drop in the affected eye or eyes two times a day.
How is Alocril® Supplied?
Alocril® (nedocromil sodium ophthalmic solution) 2% is supplied in a sterile white ophthalmic dispensing bottle with 5mL in a 10mL bottle.